SUCCESS OF PREGNANCY AND CHILDBIRTH IN SYNDROME HERLYN-WERNER-WUNDERLICH (HWW)/ SYNDROME OHVIRA: LAPORAN KASUS LANGKA
DOI:
https://doi.org/10.70248/jophs.v3i2.3943Keywords:
OHVIRA, Müllerian duct, DidelphysAbstract
Herlyn-Werner-Wunderlich (HWW) syndrome also known as OHVIRA (Obstructed HemiVagina and Ipsilateral Renal Agenesis) syndrome is a rare form of Müllerian Duct Anomalies (MDA). Uterine malformations may be associated with adverse obstetric outcomes, including increased rates of miscarriage, malpresentation, and preterm birth. Case Illustration: A 29-year-old woman at 36-37 weeks' gestation was diagnosed with Premature Rupture of Membranes with OHVIRA syndrome. The patient underwent a cesarean section under spinal anesthesia. A baby girl was born with a birth weight of 2980 grams and an Apgar score of 8/9. The uterus appeared didelphysic. Discussion: This case study examines a nulliparous woman with premature rupture of membranes
(PROM) and OHVIRA syndrome. Delivery was assisted by cesarean section. Conclusion: OHVIRA syndrome is a rare condition that carries many risks in pregnancy. However, there have been several cases of successful pregnancies and deliveries. Suggestion: A multidisciplinary approach and patient education are needed to increase the success of pregnancy and childbirth.
References
Aljahdali EA, Sharafuddin LI, Baamer WO, Enani MA, Alzhrani FS. Successful pregnancies in an adolescent with Herlyn-Werner-Wunderlich ( HWW ) syndrome : a case report and literature review. Ann Pediatr Surg [Internet]. 2022;18(34):1–7. Available from: https://doi.org/10.1186/s43159-022-00171-6
Yoshihara T, Okuda Y, Yoshino O. Association of congenital uterine anomaly with abnormal placental cord insertion and adverse pregnancy complications a retrospective cohort study. J Matern neonaTal Med [Internet]. 2024;37(1):1–5. Available from: https://www.tandfonline.com/doi/epdf/10.1080/14767058.2024.2382309?needAccess=true
Kang J, Qiao J. Impact of congenital uterine anomalies on reproductive outcomes of IVF / ICSI ‑ embryo transfer : a retrospective study. Eur J Med Res [Internet]. 2024;29(48):1–10. Available from:
https://doi.org/10.1186/s40001-023-01544-2
Triantoro NA, Pangastuti N. Diagnosis and Treatment in Patient With Herlyn-Werner- Wunderlich Syndrome : A Case Causing Pelvic Pain. J Kesehat Reproduksi [Internet]. 2021;8(3):144–8. Available from: https://journal.ugm.ac.id/jkr/article/view/64831/34221
Kueppers J, Wehrli L, Zundel S, Shavit S, Stahr N, Szavay PO. Journal of Pediatric Surgery Case Reports OHVIRA-syndrome in a newborn. J Pediatr Surg Case Reports [Internet]. 2021;69:1–5. Available from: https://doi.org/10.1016/j.epsc.2021.101859
Tomecka P, Jagodzinski A, Luczak J, Waszczuk L, Murawski M. Diagnostic Challenges of OHVIRA Syndrome — A Case Report. J Clin Med [Internet]. 2026;15(190):1–8. Available from: https://www.mdpi.com/2077-
/15/1/190
Hakim S, Kadarusman AKP, Fadhly RA, Suryoadji KA, Hadinata V, Zahra R, et al. PENDEKATAN DIAGNOSIS SINDROM OHVIRA PADA FASILITAS KESEHATAN TERBATAS: SEBUAH TINJAUAN SISTEMATIS. J Ilm Kesehat [Internet]. 2024;23(3):139–44. Available from: https://www.researchgate.net/publication/388567796_PENDEKATAN_DI AGNOSIS_SINDROM_OHVIRA_PADA_FASILITAS_KESEHATAN_T
ERBATAS_SEBUAH_TINJAUAN_SISTEMATIS
Bhamidipaty-pelosi S, Kyei-barffour I, Volpert M, Neill NO, Grimshaw A, Eriksson L, et al. Müllerian anomalies and endometriosis : associations and phenotypic variations. Reprod Biol Endocrinol [Internet]. 2024;22(157):1– 15. Available from: https://link.springer.com/article/10.1186/s12958-024- 01336-1?error=cookies_not_supported&code=9e24a932-811c-468e-850f 2da5418e2573
